Zinc Phosphide Poisoning from A To Z .

Document Type : Review Article

Authors

1 forensic medicine and clinical toxicology, faculty of medicine , port said university, Egypt.

2 Vice Dean for postgraduate studies , faculty of medicine , Port Said University

3 Instructor of forensic medicine and clinical toxicology faculty of medicine port said university.

Abstract

Toxicity from rodenticides as metal phosphides is common in the whole world, Suicidal behaviors are the most frequent cause of poisoning, followed by unintentional exposure. The average age is close to 21.
Zinc phosphide is a Gray crystalline substance or gray black powder. it isa popular domestic rodenticide due to its accessibility, low cost and high availability.
Phosphides become hazardous quickly after consumption, usually within 30 minutes.
It enters the body and is transformed into phosphine gas upon consumption.
Phosphine works by inhibiting cytochrome oxidase, which impairs mitochondrial function. Apart from causing cell energy failure, free radical.
Metal phosphide poisoning results in cyanosis, hypotension, shock, palpitations, nausea, restlessness, stomach discomfort, and cardiac arrhythmias, Hepatitis, acute tubular necrosis, disseminated intravascular coagulation, and pulmonary alkalosis are additional uncommon side effects.
Since there is sadly no known antidote to lower the high death rate, it is crucial to identify these patients and treat them as soon as possible.

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Medicine Updates
Volume 16, Issue 16
January 2024
Pages 64-71

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